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The mighty mice prove pluripotency for iPSCs Free
Duanqing Pei*
Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510663, China *Correspondence to:Duanqing Pei, Tel: +86-20-3229-0706; Fax: +86-20-3229-0606; E-mail: pei_duanqing@gibh.ac.cn
J Mol Cell Biol, Volume 2, Issue 4, August 2010, 171-172,  https://doi.org/10.1093/jmcb/mjp055

By injecting induced pluripotent stem cells (iPSCs) into tetraploid blastocysts to generate live pups, two groups in China demonstrated that the injected cells are as pluripotent as embryonic stem cells, i.e. capable of giving rise to every cell in the newborn mice. This achievement validates iPS technology for regenerative medicine.